Functional Nutrition & Integrative Health Center

Dr. John Heary
266 Buffalo St., Hamburg, NY 14075
(716) 545-4090

This Skin Condition Can Be a Sign of Diabetes

Darkening of the skin at the nape of the neck could be an early indication of insulin resistance and diabetes.

The condition, called Acanthosis Nigricans (AN), is marked by the darkening and thickening of the skin on the sides or back of the neck, the armpits, under the breast, and groin.

Acanthosis Nigricans is a skin condition that signals high insulin levels in the body.

Acanthosis Nigricans is important because these markings can help identify persons who run the risk of developing diabetes in the future.

Once identified, the necessary measures to lower the insulin levels and reduce the risk of developing diabetes can be taken.

Similarly, the acanthosis nigricans markers will begin to fade.

Acanthosis nigricans is a skin manifestation of insulin resistance and an early indication of diabetes," says Dr Anoop Misra, professor of medicine at the All India Institute of Medical Sciences (AIIMS), New Delhi.

Dr. Misra's study followed adult patients with acanthosis nigricans who had no history of diabetes and discover that 58% of the patients reviewed had the metabolic syndrome. In fact 24% had full-blown diabetes.

All were clueless about their diabetic status.

Who is Dr. Anoop Misra?

Dr Misra is considered as a lead researcher internationally for insulin resistance, diabetes mellitus, hyperlipidemia and obesity in the Indian population. He has substantially contributed to the understanding of the mechanisms, prevention and management of obesity and diabetes mellitus in Indians by publishing more than 100 papers in the international journals, and debating on important issues in the International conferences. He has worked as the World Health Organization fellow at Royal Free Medical School, London and University of Texas Southwestern Medical Center at Dallas. He also worked as faculty in Internal Medicine and Endocrinology at the prestigious University of Texas Southwestern Medical Center at Dallas.

References:

Reinehr T. Clinical presentation of type 2 diabetes mellitus in children and adolescents. Int J Obes (Lond). 2005 Sep;29 Suppl 2:S105-10.
Charnvises K, Weerakiet S, Tingthanatikul Y, Wansumrith S, Chanprasertyothin S, Rojanasakul A. Acanthosis nigricans: clinical predictor of abnormal glucose tolerance in Asian women with polycystic ovary syndrome. Gynecol Endocrinol. 2005 Sep;21(3):161-4.
Mohrenschlager M, Ring J, Kohn FM.Diabetes mellitus: [Cutaneous and mucosal marker lesions] MMW Fortschr Med. 2005 Oct 6;147(40):34-6.
Bolding J, Wratchford T, Perkins K, Ogershok P.Prevalence of obesity, acanthosis nigricans and hyperinsulinemia in an adolescent clinic. W V Med J. 2005 May-Jun;101(3):112-5.
Grandhe NP, Bhansali A, Dogra S, Kumar B.Acanthosis nigricans: relation with type 2 diabetes mellitus, anthropometric variables, and body mass in Indians.
Postgrad Med J. 2005 Aug;81(958):541-4.
Flagothier C, Quatresooz P, Bourguignon R, Pierard-Franchimont C, Pierard GE. Abstract [Cutaneous stigmata of diabetes mellitus] Rev Med Liege. 2005 May-Jun;60(5-6):553-9.
Compliments of Functional Medicine University

Type 2 Diabetes

Diabetes is a chronic disorder marked by increased blood sugar (glucose). Complications often develop
including heart disease (such as heart failure), vascular diseases (including hypertension, heart attack, stroke),
poor circulation (causing problems such as foot ulcers), eye damage (retinopathy that can lead to blindness),
kidney disease (progressing to kidney failure), bone fractures, arthritis, various types of cancer, increased
inflammation without resolution, poor healing, dental disease, loss of cognitive function, neuropathy (nerve
damage) and depression. Type 1 (‘juvenile’ or ‘insulin-dependent’) diabetes occurs when the pancreas does
not produce enough insulin. Type 2 diabetes (T2D) occurs when the body produces insulin but it doesn’t work
well—it is unable to process glucose appropriately or lower glucose levels effectively due to insulin resistance.
T2D used to be referred to as ‘adult-onset’ diabetes but it is becoming more common in children and teenagers
as well as adults of all ages. It now accounts for 90% to 95% of all diabetes. Glucose, the end product of
carbohydrate digestion, is needed by cells for energy and growth. Insulin helps glucose (and some fats and
proteins) enter cells for either oxidation (burning) or storage (of excess glucose as glycogen in the liver). With
insulin resistance, glucose can’t properly enter cells. Instead of the cells using glucose as fuel, it builds up in
the bloodstream, leading to hyperglycemia (high blood sugar). For a while, the pancreatic beta-cells pump out
more insulin to compensate for the added demand so blood sugar levels stay under control. But eventually the
pancreas can’t keep up and the body tips over into diabetes. As insulin output falls, blood sugar climbs. 1 T2D
is now defined as an epidemic. The number of North Americans afflicted is now more than double what it was
in 1991. At the beginning of 2011, there were approximately 25.8 million children and adults in the US (8.3% of
the population) with diabetes. Another 25% of the population has pre-diabetes. However, the definition of T2D
has changed over the years. For example, in the 1970s a fasting blood sugar over 140 resulted in a diagnosis;
in 1997 it was decided that a fasting blood sugar over 126 was diabetes. That ‘little’ alteration converted over
1.6 million people into diabetics. Medical treatment guidelines have also changed strikingly since the 1980s. 2
TESTS. Glycated hemoglobin (HbA1c), a measure of long-term average blood sugar, was previously used
only to monitor glucose control, but is now used to diagnose diabetes. A level of 6.5% or higher is thought to
indicate diabetes. However, one sample does not tell the whole story; interferences occur that can cause a
deceptive result. Also, “the optimum HbA1c seems to vary between patients.” A glucose tolerance test is
usually used and/or random glucose, fasting glucose, and 2-hour glucose concentrations after an oral glucose
(a refined sugar) challenge. Some people who don’t have diabetes react with a blood sugar spike. A 2012
study found that screening people at risk didn’t reduce all-cause, cardiovascular, or diabetes-related mortality
within 10 years. So “benefits of screening might be smaller than expected...” The recommended systolic blood
pressure ceiling of 130 mm Hg was recently raised to 140 mm Hg due to an analysis showing that intensive
blood pressure control (with drugs) did not decrease deaths or heart attacks and only slightly lowered risk of
stroke. 3
In the beginning stages of diabetes, many people have no symptoms or mild symptoms that aren’t
suspected of being diabetes. Symptoms may include: increased thirst, increased hunger, increased urination
(especially at night), sores that don’t heal, fatigue, unaccounted-for weight loss, blurred vision. Although T2D
was thought to involve genetic components, it is becoming clear that, if genes are involved, it is epigenetic
modifications—factors that turn genes on or off—that create the tendency. Epigenetic influences are primarily
environmental including diet, activity levels, chemical exposures, medications, etc. 3
CAUSES. There are many risk factors including poor diet, mother’s diet, a sedentary lifestyle, impaired glucose
tolerance, family history of diabetes, high blood pressure, and others. But the leading cause of T2D is excess
weight or obesity—being overfed but undernourished, over-agitated but underactive. 4 Approximately 80% of
people with T2D are overweight or obese. Eating too much (often due to inadequate nutritional value of the
foods—really, nonfoods) results in more fat storage as subcutaneous fat (beneath the skin) and visceral fat (in
and around organs and tissues such as the liver, heart, muscles, digestive tract. Notably, “excess visceral fat
and insulin resistance, but not general adiposity [excess fat], were independently associated” with pre-diabetes
and T2D. Fat tissue is distributed differently than it is in people without diabetes. Excess stored fat may block
2
an insulin-signaled glucose transporter that normally ferries blood sugar into the cells. 5 Excess liver fat can be
an even better predictor of metabolic dysfunction than visceral fat. It may explain why even a modest drop in
weight can lower fasting blood sugar levels with no change in muscle fat. With some weight loss, the liver
responds better to whatever insulin is made, sometimes enough to control glucose metabolism. The liver is
one of the most metabolically active organs in the body. Among its many functions are bile production (to
emulsify fats), conversion of monosaccharides to glucose, storage of glucose until its energy is needed,
deamination of excess amino acids for use in energy production, detoxification, synthesis of lipoproteins and
cholesterol for transport of fat to tissues, and conversion of fatty acids to ketones or acetyl groups for use as
energy sources. The liver may play a larger role in blood sugar metabolism than the pancreas. 6
Numerous toxins can play a role in causing or worsening T2D such as: inorganic arsenic, persistent organic
pollutants (such as pesticides that accumulate in the environment), bisphenol A and phthalates (from plastics),
dioxins, fresh-water fish contaminated with DDE (major breakdown product of DDT), and a number of organophosphate pesticides. 7 Avoiding toxic exposures and periodic detoxification programs may help. Various drugs
can increase T2D risk including antidepressants, ADHD medications and statins. Some drugs can worsen
diabetes by interfering with insulin or blood sugar levels, including: diuretics, over-the-counter decongestants,
steroids (cortisone, prednisone) and beta-blockers. Others can alter effects of diabetes medications.
8
MEDICAL TREATMENT. Gastric bypass surgery for the obese may lower blood sugar and eliminate the need
for diabetes drugs. But nutrient deficiencies and other complications can develop. There are many antidiabetes
drugs. Some stimulate the pancreas to produce more insulin. Others work on the liver to decrease the amount
of sugar released into the blood. Some are “insulin sensitizers” that attempt to make cells more sensitive to
available insulin. Starch-blocking drugs slow carbohydrate digestion. The popular Metformin lowers blood fat
levels and attempts to prevent the body from producing more sugar. Insulin lowers blood sugar though this
does not address the underlying cause of T2D. Actually, none of the drugs approach underlying causes; they
don’t cure diabetes and have many side effects. There is no evidence that the drugs currently available reduce
risks of long-term complications such as heart disease, stroke, peripheral vascular disease, kidney disease,
retinopathy, or others. Some actually increase risks, including thiazolidinediones (Avandia, Avandaryl, Duetact
or Actos) which increase heart attack rate 43% and increase heart failure risk. Some drugs raise fracture,
anemia and macular edema risks. Most drugs are associated with a greater risk of death from any cause. All
(except Metformin) can contribute to more weight gain and further increases in insulin resistance; one of the
worst is insulin. Metformin can cause vitamin B12 deficiency. Other drugs lead to deficiencies such as folate or
CoQ10. Some drugs increase risk of pancreatitis and cancers such as bladder or pancreatic cancer. Only
about 40% of patients reach target blood sugar levels with standard therapies; many remain uncontrolled or
progress to inadequate control over time. Most people take 2 or 3 diabetes drugs. A new drug type (Invokana)
poses serious risks (falls, dehydration, cardiovascular events, dizziness, renal impairment) that outweigh its
limited benefits. 9 Tight control of blood pressure and cholesterol with drugs increases risk of death. Aggressive
blood-sugar lowering produces only minor benefits and may cause serious drops in blood sugar that can harm
the brain, cardiovascular system, increase risk of death, and more. The intensity of medical treatment needed
“almost certainly varies between individuals;” blood sugar and other targets should be individualized. “Good
glucose control is a potentially life-saving intervention,” says Edwin AM Gale, MD, “but it remains to be
determined what we should use, when, and how vigorously we should use it, and for how long.” 10
LIFESTYLE. Lifestyle is the foremost and often only cause of T2D. Studies show that intensive lifestyle
intervention is very effective in preventing T2D and improving the health of people with diabetes. Early
diabetes can be overcome. Because T2D “is largely rooted in reversible social and lifestyle factors, a medical
approach alone is unlikely to be the solution.” Sadly, in “this respect, medicine might be winning the battle of
glucose control, but is losing the war against diabetes.” Dr Osama Hamdy, MD, PhD, a medical director in
Boston, stated: “We’ve been treating diabetes for 40 years by adding more and more medications, with no big
improvements. But if you act early, keep the weight off, and maintain a healthy lifestyle, you can put this
disease in remission forever.” Research supports “the idea that significant improvements in health may be
attained through lifestyle adjustments.” 11 A healthful diet and exercise have been shown to beat drugs for
improving fitness, glycemic control, insulin sensitivity, blood fats and cardiovascular risk factors. Exercise
quickly lowers blood sugar. When muscles are exercising, glucose and other nutrients can enter muscle cells
3
even in the absence of insulin. Both aerobic and resistance (weight training) exercises reduce HbA1c, improve
insulin resistance and glycemic control, increase muscle mass, decrease artery-wall thickening and reduce
adiposity. Poor sleep patterns or sleep deprivation can impair glucose metabolism and lower control of blood
sugar levels; improving sleep patterns improves long-term outcomes. 12 Diet, exercise and improved sleep are
all important for significant weight loss which improves glycemic control, insulin sensitivity and cardiovascular
risk factors and lessens or eliminates the need for drugs to lower blood sugar, blood pressure and blood fats. 13
DIET. T2D is associated with modern processed-foods; it is rarely seen in cultures relying on a more traditional
diet and way of life. Eating whole natural foods (predominantly organic and non-GMO) to optimize nutrient
status can have profound effects. The quality and source of foods influence all biological systems involved in
insulin resistance and T2D.
14 Avoid: refined sugars like sucrose, corn syrup, high-fructose corn syrup; soda
and other refined and highly-processed items including white rice, white bread, processed meats, refined salt,
and the like. Artificial sweeteners disturb areas of the brain that control appetite and satiety and cause other
imbalances. Include: plenty of fresh vegetables and fruit (restricting fruit does not improve glycemic control),
legumes (lower glucose and insulin), whole grains, nuts and seeds (help glucose control, reduce HbA1c and
LDL cholesterol), and dairy products (certified raw milk products, yogurt and aged cheeses are best; whey
reduces post-meal blood sugar spikes). There is a direct link between fiber—soluble and insoluble—and the
glycemic response to specific foods. Foods containing fiber are vegetables, fruits, whole grains and legumes;
fiber supplements such as inulin or psyllium are also helpful. The recommended amount of fiber is 25 to 35
grams per day; few Americans consume that much. Many traditional cultures ate 3 to 5 times as much.
15
There is a huge difference between natural, whole nutrient-dense foods and refined, over-processed, bogus,
chemicalized nonfoods. The latter are often loaded with added refined or artificial sweeteners and other refined
carbohydrates, contain various artificial ingredients, are low in nutrients, low in fiber, usually digested quickly
so fewer calories are burned, often contain altered or refined or fake fats, and tend to be addictive (leading to
overconsumption). The American Diabetes Association recently updated its nutrition guidelines for diabetics.
Rather than a one-size-fits-all diet, the new recommendations favor individualized plans that take into account
a person’s lifestyle and metabolic needs. Previously a diabetic diet dictated how many grams of carbohydrates,
protein and fats that should be consumed each day based on the person’s weight. It is now conceded that
there is no ideal amount of these nutrients for everyone and each person should have a dietary strategy that is
best suited for him or her. Whole grains, fruits, vegetables, legumes and dairy products provide carbohydrates
that are less likely to produce spikes in blood glucose levels. Foods and beverages that contain added refined
sugars, refined grains, etc. are “more likely to cause fluctuations in blood glucose and they are often ‘empty
calorie’ foods that contribute little or nothing in the way of valuable nutrients.”
16 No news to us.
Protein/Fat/Carbohydrates. Research results regarding high-protein, high-fat or high-carbohydrate diets versus
low-protein, low-fat or low-carbohydrate diets vary. Some studies show that a low-carbohydrate, high-protein
diet improves glycemic control, improves insulin sensitivity, increases plasma glucagon, lowers insulin and
triglycerides. But fiber intake is low. 17 Other studies find that low-carbohydrate Mediterranean-style diets result
in better glycemic control and less need for diabetic drugs than low-fat diets.
18 Some studies show that high
carbohydrate, low protein and moderate or low fat diets improve glycemic control and insulin resistance. Lowfat vegetarian diets (that restrict refined sugars) can lower fasting glucose, weight, blood pressure, HbA1c, total
and LDL cholesterol. Some research indicates that consumption of excess fat impairs insulin receptors. Other
studies report that eating lots of red meat—especially processed meats—increases T2D risk. A low-fat, highfiber diet may promote weight loss without causing unfavorable alterations in blood fats or glycemic control. 19
Natural, unaltered fats (such as fish, nuts, unrefined oils, butter) can reduce blood sugar and insulin levels.
Omega-3 fats are beneficial, no doubt because most people consume excessive omega-6 fats from refined
vegetable oils and commercial meats that contain less omega-3s than pasture-raised meats. Some research
condemns saturated fats; others simply condemn high amounts of fats. There is research showing that either
low-fat diets don’t cause adverse glycemic effects or do cause adverse glycemic effects. Mary G Enig, PhD,
explains that, in most studies, the actual amount of saturated or polyunsaturated or trans fats in diets is not
measured. What occurs to people who eat a diet high in natural saturated fats compared to those eating a lot
of refined vegetable oils is not explored. “Saturated fats have no effect when appropriate comparisons are
made.” T2D was unheard of a hundred years ago when people’s diets were rich in saturated fats. When people
eat less saturated fat, they end up eating more detrimental trans-fats. Trans fats are being eliminated from
4
processed foods but are often replaced by just-as-bad contrived fats.
20 The amount of carbohydrates, protein
and fat needed vary with the individual. “The nutrient composition of the diet should be individualized…” 21
Acidosis and intolerances. Russell M Jaffe, MD, PhD, shows that, when people with T2D eat foods that provide
insufficient minerals to buffer metabolic acids, cellular alkaline reserves are gradually depleted. Deficits of
buffering minerals (magnesium, potassium, zinc, and others) result in intracellular metabolic acidosis that
causes reduced cellular energy production and impaired toxin removal. Intolerances can develop to just about
any food, chemical or contaminant, causing immediate or delayed reactions. When the body is imbalanced,
distressed, suffering a large toxic load or deficient in needed nutrients, it cannot respond healthfully or properly
to substances. A Health Studies Collegium study evaluated sensitivities to environmental chemicals, foods and
food additives in diabetics. By avoiding reactant items and developing an individualized natural, nutrient-rich,
repair-stimulating diet, participants experienced significant benefits such as decreased insulin and HbA1c.
Control subjects receiving only American Diabetes Association guidelines had much less benefit. Reducing
toxic load, immune load, neurohormonal distress and gastrointestinal irritants plus providing sufficient nutrients
and foods for detoxification and healing processes improve diabetic control. Increased intestinal permeability
(leaky gut) can occur from insults or injuries (from processed nonfoods, drugs, toxins), maldigestion and repair
deficits. Avoiding reactant foods is the first step to reduce leaky gut; providing foods and nutrients to support
repair and healing is next.
22 Dr Patrick Kingsley finds that diabetics “inadvertently eat certain foods on a fairly
regular basis that cause their blood sugar to go up too high.” These foods are identified and eliminated from
the diet. A three-week elimination diet, then reintroduction (one food at a time) identifies such items. When
reintroducing a food, a blood sugar measurement should be taken first thing in the morning; then the food
should be consumed for breakfast followed by another blood sugar measurement an hour later. Do not test a
food if the blood sugar is already high before breakfast. William Philpott MD treats diabetics by identifying
foods that individually raise blood sugar levels, then supplying needed nutrients and digestive support. 23
GLYCEMIC INDEX. Some doctors recommend eating only foods rated low on the glycemic index (GI). Others
question the GI validity. Some endorse using the glycemic load (GL) instead. The GI only indicates how fast a
single food turns into blood sugar. It doesn’t take into account how much of the food is eaten or that foods are
rarely eaten alone; eating some protein and/or fat with a carbohydrate greatly lowers its GI effect. The GL is a
calculation of the GI multiplied by the amount of carbohydrate in a serving and divided by 100; it takes into
account the GI, the amount of carbohydrate, and how both impact blood sugar. For example, both white bread
and carrots have high GI numbers. But the GL of 2 slices of white bread is more than 5 times higher than the
GL of ½ cup of carrots. 24 Some nutrient-rich foods are rated as high-GI while some nutrient-poor foods are
rated as low-GI. For instance, sugared chocolate has a lower GI than oatmeal. White potatoes are high on the
GI, yet eating other vegetables and a protein with them slows digestion and lowers the GI. Also, the effect of a
food varies from person to person. “Measurements of GI and GL can vary depending on who’s doing the
testing, and studies have shown that the actual effects of foods on blood sugar vary by individuals.” One study
compared glycemic effects of 50 grams of white bread on healthy adults. The average GI was 78 for the first
test, 60 for the second and 75 for the third. Values varied 17.8% between individuals and 42.8% within
individual scores from one test to another. 25 In 2008, researchers compiled a new set of GI guidelines. Some
of their conclusions oppose other research. For example, they rated whole wheat foods high and refined pasta
low, the opposite of earlier GI versions. Many studies show that people who eat whole grains are less likely to
develop T2D.
22 So the “wise approach…is for patients to know their glucose response to eating certain meals.
Self-monitoring of blood glucose postprandially [after meals] may become more about understanding the
patient’s response to food than monitoring the disease.” This is testing for individual intolerances. There is little
agreement about the role of the GI in managing diabetes and whether it influences the risk of diabetes. 26
SPECIFIC NUTRIENTS. Numerous studies have found alterations in micronutrient status of people with T2D.
There is confusion concerning specific requirements since studies are contradictory depending on the people
studied. Confusion is not surprising since people are not viewed in accordance with biochemical and metabolic
individuality. If supplements are used, they are often isolated or synthetic ‘nutrients’ which also confuse since
such separated/contrived compounds don’t provide the interacting, integrated, multi-nutrient complexes of real
foods. For a specific complication, a more pharmacological approach using single nutrients may be needed for
a limited time; whole foods are superior sustenance. Nutrients consistently found to be involved in T2D include:
5
Nutrient: Supports, improves or helps:
Chromium 27 Weight reduction, insulin sensitivity, glucose metabolism, HbA1c, lipid variables,
cardiovascular function. Adding biotin improves function. Deficiency common.
Magnesium 28 Nerve/ muscle pain, hypertension, cardiovascular disease, kidney disease, retinopathy,
insulin resistance, carbohydrate metabolism, enzymatic reactions. Deficiency common.
Calcium 29 Insulin sensitivity, T2D risk; vitamin D optimizes glucose metabolism effect.
Selenium 30 Cardiomyopathy, cardiovascular disease, neuropathy, glucose metabolism. Tends to be
deficient. Large isolated doses can cause variations in blood sugar levels.
Potassium 31 Insulin resistance, peripheral insulin levels. Depletion common. Avoid large doses.
Vanadium 32 Blood sugar and HbA1c levels without hypoglycemia, frequent urination, thirst, fatigue,
sugar cravings. Mimics insulin. Food sources best.
Zinc 33 Organ damage, albumin excretion (re: kidney), cardiovascular disease, HbA1c. Needed
to convert B6 to active form, P5P. Component of insulin. Deficiency common.
Copper 33 Superoxide dismutase activity, glucose tolerance, lipid peroxidation, HbA1c, insulin level.
Manganese 34 Mitochondria membranes, function. Hyperglycemic tissue damage. Often deficient.
Vitamin A 35 Insulin release from pancreas, retinopathy, kidney problems, neuropathy, slowness to
heal, excess inflammation. Large synthetic doses can inhibit insulin release.
Carotenoids 35 Glucose metabolism, retinopathy. Enzymes to convert into vitamin A may be
deficient in diabetic pancreas.
Vitamin E 36 Glucose control, insulin action, cell membranes, tissue damage, HbA1c, blood vessel
integrity, neuropathy. Isolated d-alpha tocopherol depletes gamma tocopherol (HbA1c).
Thiamine (B1) 37 Damage to nerves, blood vessels, eyes, kidneys. Blood vessel dilation, cardiovascular
disease, carbohydrate breakdown, glucose metabolism enzymes. Deficiency common.
Riboflavin (B2) 38 Glutathione regeneration for detoxification of reactive oxygen species.
Niacinamide (B3) 39 Production of glucose tolerance factor.
Pyridoxal-5-phosphate Amino acid, fat and carbohydrate metabolism. Inhibits linkage of glucose molecules
(B6) 40 to proteins including albumin. Often deficient.
Folate 40 With B12 and B6, lowers elevated homocysteine which can be caused by Metformin.
B12
40 With folate and B6, lowers elevated homocysteine. Neuropathy symptoms, foot ulcers,
kidney disease. Often deficient. Metformin depletes B12.
Biotin 41 Cofactor for glucokinase re: intracellular glucose metabolism, triglycerides.
Inositol 42 Glycemic control by mediating insulin action. Adds to chromium’s effects.
Vitamin C 43 Blood vessel integrity, kidney function, lymphocyte levels. Ascorbic acid alone may
increase cardiovascular risks. Flavonoids: insulin resistance, inflammatory biomarkers.
Vitamin D 44 Blood vessel and nerve function, inflammation and repair.
Amino acids 45 Leucine: insulin secretion, protein synthesis, glycemic control. Glutamine: hormones
Involved in meal-related insulin secretion. Creatine: glycemic control. L-carnitine: insulin
sensitivity, cellular glucose uptake, nerve conduction and regeneration, glycation.
Omega-3 fatty acids Insulin resistance, homocysteine levels, inflammation, depression risk, blood sugar
46 levels, HbA1C, blood-vessel-lining function, blood flow, triglycerides, cholesterol.
CLA 46 (Conjugated linoleic acid). Blood sugar levels. In meats and dairy products.
GLA 46
 (Gamma linolenic acid). An omega-6. Glycemic control.
CoQ10 47
 (Coenzyme Q-10). Often low. Glycemic control, neuropathy, blood vessel function.
ALA 48 Convert glucose into ATP. Insulin sensitivity, glucose tolerance, post-meal and fasting
(Alpha-lipoic acid) glucose, glutathione levels, HbA1c, cardiovascular & kidney complications, neuropathy.
Gut bacteria 49 Often imbalanced; composition tends to be different in diabetics.
Among the many herbs found to assist blood sugar control, insulin production or release, HbA1c levels, insulin
resistance, triglyceride and cholesterol levels are: Gymnema (if taken with anti-diabetic drugs, glucose levels
may drop significantly), cinnamon (most studied form is cassia; avoid huge doses; ¼ to ½ teaspoon per day
okay), mate tea, berberine (isolated from rhizome Huanglian or goldthread), ginger, fenugreek, curcumin
(extracted from turmeric), Bitter Melon, ginseng (also helps cardiovascular risks). Billberry and ginkgo aid
retinopathy, blood flow, blood vessel function, kidney disease. In addition to helping to lower fasting glucose,
HgA1c, cholesterol & triglycerides, silymarin, (milk thistle extract), lowers liver SGOT and SGPT elevations.
50
6
Supplemental support for the person at risk for T2D can vary, but a foundational schedule may include:
Just Before Two Meals: After Two Meals:
1 Hepatrophin PMG (chew), liver support 1 Cod Liver Oil, omega 3s, vitamins A and D
2 Cataplex B (chew), B vitamins 1 Betafood (chew), ALA, aid nitric acid production
1 Cataplex G (chew), B vitamins 1 Cellular Vitality, CoQ10, B vitamins
1 Cataplex GTF (chew), chromium, pancreas support 1 SP GreenFood, carotenes, ALA, Mg, K, etc.
1 Cataplex C (chew), vitamin C complex 1 Wheat Germ Oil, vitamin E complex
Twice per day: 1 Gymnema (Medi-Herb)
________________________________________________________________________________________
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 Novel Stool Test Enhances Colon Cancer Detection. 

Researchers from the Netherlands Cancer Institute have developed a new diagnostic called the multitargetFIT-test that examines stool
samples for hemoglobin and two proteins to more accurately identify early-stage colon cancer tumors, both
reducing healthcare costs and saving lives. 

The Lancet Oncology, February 2024
Plant-Based Diet May Counter Some Prostate Cancer Treatment Side Effects. 

An analysis of data
concerning more than 3,500 patients under treatment for prostate cancer found that those who consumed a
plant-based diet were less likely to experience erectile dysfunction, urinary incontinence, and hormonal symptoms. 

Cancer, February 2024
Smoking Overtakes Injection as Leading Cause of Drug Overdose Deaths. 

The Centers for Disease Control and Prevention reports that since January 2020, overdose deaths linked to smoking drugs
(particularly fentanyl) have increased 73.7% and the practice is now the primary avenue for drug overdose deaths.
The finding highlights the necessity for evolving strategies in combatting the ongoing drug overdose epidemic in the
United States. 

Morbidity and Mortality Weekly Report, February 2024
Prehabilitation Cuts Risk for Post-Operative Complications. 

For patients scheduled to undergo
major abdominal surgery, a recent meta-analysis that included 20 studies found that participating in a
prehabilitation exercise program to improve physical fitness reduced the risk for post-operative complications by 20%. 

Journal of Clinical Anesthesia, June 2023
Fasting May Protect Against Chronic Inflammation. 

Chronic inflammation has been linked with
several poor health outcomes, including cardiovascular disease. A recent experiment found that fasting
increases arachidonic acid levels in the body, which inhibits a protein— NLRP3 inflammasome—associated
with chronic inflammation. 

Cell Reports, February 2024
Combat Allergies with Fiber? 

A recent experiment revealed that the breakdown of fiber in the gut can
produce short-chain fatty acids such as butyric acid and valeric acid that help to inhibit histamine release, which
can aid in managing allergies. 

Journal of Immunology, January 2024
 Nitrite Additives Linked to Type 2 Diabetes. 

Using data from the NutriNet-Santé study, researchers
report that a higher intake of nitrite food additives is associated with an increased risk for type 2 diabetes. The
researchers add, “These results provide a new piece of evidence in the context of current discussions regarding
the need for a reduction of nitrite additives' use in processed meats by the food industry, and could support the
need for better regulation of soil contamination by fertilizers. In the meantime, several public health authorities
worldwide already recommend citizens to limit their consumption of foods containing controversial additives,
including sodium nitrite.” 

PLOS Medicine, January 2023
Try an Activity Tracker. 

Central Queensland University’s Dr. Corneel Vandelanotte notes that
activity trackers can act as a useful tool to help an individual become more physically active and to reach their
fitness goals. Dr. Vandelanotte adds that while there are sophisticated devices that can track resting heart rate,
heart rate during exercise, maximal heart rate, and VO2 max, a basic activity tracker that can monitor total steps
and activity minutes will suffice for most people. 

The Conversation, January 2024
 Living in a “Food Swamp” May Raise Stroke Risk. 

A food swamp is an area with numerous unhealthy
food options and few grocery stores. A study that included 17,875 adults entering old age revealed that living in
a food swamp is associated with a 13% higher risk for stroke. 

American Stroke Association, February 2023 
Anxiety Can Worsen Outcomes for Diabetic Kidney Disease Patients. 

Among a group of 403 patients with diabetic kidney disease, researchers found that those who had also been diagnosed with
anxiety disorder were 53% more likely to experience a worse progression in kidney function over the following three years. 

Renal Failure, January 2023
Regular Exercise at Midlife Lowers Future Stroke and Dementia Risk. 

Using data from the Atherosclerosis Risk in Communities study, researchers report that participants who regularly
exercised at midlife had better cardiovascular and cerebrovascular health two decades later, which is associated
with a reduced risk for stroke and dementia. 

American Stroke Association, February 2023
Health Benefits of Eating Fish. 

Healthline reports that fish is high in important nutrients, and regularly
eating fish may lower the risk of heart attack and stroke, aid fetal and infant development, boost brain health,
improve vitamin D status and sleep quality, reduce the risk for autoimmune diseases and asthma, and protect
vision in old age. 

Healthline, January 2023
 Where to Eat a Healthy Lunch at Work… 

A survey of 622 workers from four companies in Tokyo
found the nutritional quality of lunches was highest when employees either ate a homemade lunch or a meal
prepared in the company cafeteria. On the other hand, when participants opted for take-out or dining at a
restaurant offsite, they were more likely to choose less healthy fare.

Journal of Occupational & Environmental Medicine, January 2024 
 Self-Compassion Can Help You Reach Weight Loss Goals. 

On the weight loss journey, it’s not uncommon to experience setbacks. A recent study found that those who use self-compassion
instead of self-criticism during these occasions are more likely to get back on track toward achieving a healthy body weight. 

Appetite, January 2024
 Sleep Apnea Associated with Weaker Bones and Teeth. 

Bone density measurements of 38
adults revealed that those with obstructive sleep apnea had significantly lower bone density than participants
without a sleep disorder. The researchers note that low oxygen levels, inflammation, and oxidative stress are
characteristic of sleep apnea and can have an effect on bone metabolism.

Journal of Craniomandibular and Sleep Practice, January 2023
Modifiable Risk Factors for Neurocognitive Disorders. 

An umbrella review that included 45 systematic reviews and 212 meta-analyses identified the following modifiable risk factors for
neurocognitive disorders, which includes mild cognitive impairment and dementia: excessive alcohol consumption, obesity, depression, diabetes mellitus, poor diet, hypertension, less educational attainment, physical inactivity, sensory loss, sleep disturbance, smoking, social isolation, traumatic brain injury, and
vitamin D deficiency. 

Dementia and Geriatric Cognitive Disorders, February 2024
Physical Exercise Boosts Motor Learning. 

University of Copenhagen researchers report that
engaging in either moderate- or high-intensity exercise before and after a motor learning session is linked to a
10% improvement in motor skill retention. The findings suggest that integrating exercise into motor skills
rehabilitation programs could lead to better outcomes for individuals recovering from illnesses and injuries that
affect their ability to move in general or engage in fine movements like writing or interacting with small objects. 

Neurobiology of Learning and Memory, November 2023
Sleeping Pills Linked to Dementia Risk. 

A long-term study that monitored nearly 3,000 older
adults for a decade found that frequent use of sleep aids is associated with up to a 79% higher risk for dementia.
Lead author Dr. Yue Leng adds, “[Further] studies are needed to confirm whether sleep medications themselves are
harmful for cognition in older adults or [if] frequent use of sleep medications is an indicator of something else that
links to an increased dementia risk.” 

Journal of Alzheimer's Disease, January 2023
Surgery Riskier for COPD Patients. 

Chronic obstructive pulmonary disease (COPD) is a chronic
lung disease that makes breathing difficult, and it is a leading cause of death in the United States. An analysis of data
concerning nearly 933,000 patients who had major surgery found that COPD is associated with a 61% greater risk of
death in the following year. Critical care specialist Dr. Mangala Narasimhan adds, “No surgery is without its risk…
For these patients, it's significantly riskier and they should consider that before jumping into a procedure… The one
piece of advice is not to ignore the underlying risks. They will catch up with you, so optimize your medical condition
prior to going into surgery.” 

Canadian Medical Association Journal, January 2023
Sore Muscles from Exercise? 

The American Academy of Family Physicians recommends the following
to manage muscle soreness following exercise: gently stretch sore muscles; apply gentle massage; use an ice pack to
reduce inflammation; use a heating pad to increase blood flow; and give the muscles time to recover before working
that body part again. 

American Academy of Family Physicians, January 2023
Toothbrushing Could Be a Life Saver in the Hospital. 

New research suggests that brushing your teeth at least once a day during a stay in the intensive care unit can reduce the risk for pneumonia
infection, leading to a lower mortality risk, shorter stay, and less time spent on a mechanical ventilator.

JAMA Internal Medicine, December 2023
Don’t Use Guilt for Exercise Motivation. 

A study involving 650 frequent exercisers found that
those with beliefs like "I am a loser if I do not succeed" were more likely to use self-pressure and guilt as
motivation, leading to a higher risk of poor mental health, including anxiety, depression, and stress.

University of Bristol, January 2024
 Coffee Consumption Linked to Healthier Liver? 

An analysis of urine samples and coffee intake data
collected from 156 middle-aged borderline-obese adults revealed that those with a higher intake of coffee were
more likely to have a healthy liver. 

Nutrients, January 2023
Uric Acid May Increase Risk for Irregular Heart Rhythm Later in Life. 

Atrial fibrillation (AFib) is a common heart rhythm disorder that can lead to stroke, heart failure, and other cardiovascular
complications. Following an analysis of 26 years of data concerning nearly 40,000 participants, researchers
report that individuals with higher uric acid levels in their blood may be up to 45% more likely to be diagnosed
with atrial fibrillation, even in the absence of high blood pressure, diabetes, coronary heart disease, or heart
failure. Researcher Dr. Elsayed Soliman adds, “This means that uric acid may not only operate through
cardiometabolic mechanisms to increase the risk of AFib, but it may also have a direct influence on AFib
development through other mechanisms.” 

Journal of the American Heart Association, January 2023
New Salt Substitute Formula Can Help Reduce High Blood Pressure. 

The National Heart, Lung, and
Blood Institute reports that a new salt formulation that is 75% sodium chloride and 25% potassium chloride can relax
the walls of the arteries, lowering blood pressure and reducing the risk for hypertension.

National Heart, Lung, and Blood Institute, December 2023
Acetaminophen Use During Pregnancy Linked to Language Delays in Children? 

New research suggests that children born to mothers who took acetaminophen during pregnancy may be at elevated
risk for delays in language development, especially among frequent users of the drug during the third trimester.

Pediatric Research, December 2023
Take Advantage of Memory Screenings. 

The Alzheimer’s Foundation of American notes
that the National Memory Screening Program offers free and confidential telehealth memory screenings to help
detect signs of cognitive decline early on when interventions may help to slow disease progression.

Alzheimer's Foundation of America, January 2024
Common Bacterial Infection and Alzheimer's Disease... 

According to a study that looked
at health outcomes of more than 4 million adults, infection from Helicobacter pylori—a bacteria that is typically
associated with indigestion, gastritis, ulcers, and stomach cancer—after age 50 is associated with an 11%
increased risk for Alzheimer's disease. 

Alzheimer's & Dementia, December 2023
Greener Neighborhoods and Stroke. 

A systematic review that included 27 studies found an
association between more greenspace in a neighborhood and both a reduced risk for stroke and improved
recovery following a stroke. The researchers speculate that these benefits may be due to the “moderating effects
of green spaces on ambient temperatures, noise and air pollution, and psychosocial health plus greater
enjoyment and opportunity for exercise and enrichment of the human microbiome.”

Journal of Neurological Sciences, January 2024
Natto Consumption Benefits Cardiovascular Health. 

Natto is a traditional Japanese food that’s made
from fermented soybeans. In a recent study, researchers observed an association between a higher intake of
natto and a healthier gut microbiome, which better regulates the production of cytokines and chemokines
associated with arteriosclerosis. 

Scientific Reports, December 2023
Bad Neighborhoods May Raise Dementia Risk. 

Using data from the Health and
Retirement Study, researchers estimate that older adults who live in troubled neighborhoods with poor social
cohesion have up to a 27% elevated risk for dementia when compared with their peers from cleaner, safer, and
more well-knit parts of town. 

Journals of Gerontology, January 2024
 Is Chronic Fatigue Syndrome Becoming More Common? 

Chronic fatigue syndrome, a
condition with no known cause, is characterized by extreme fatigue that fails to improve with rest. Using data
from a survey of nearly 57,000 Americans, researchers estimate that 3.3 million adults in the United States may
have chronic fatigue syndrome, a marked increase from previous estimates ranging from 836,000 to 2.5 million
American adults. 

NCHS Data Brief, December 2023 
Latin Dance for Health. 

In a recent article published in BMC Public Health, Dr. Susan Aguiñaga
notes the lively rhythms of salsa, merengue, bachata, and other Latin dances offer a great way to engage in
physical activity that not only promotes physical health but can provide mental health benefits such as social
connection, stress reduction, better mood, and improved memory. 

BMC Public Health, December 2023
Is Vitamin B12 a Key Player in Cellular Reprogramming? 

Cellular reprogramming is a process in
which existing cells transition into another type of cell. In a recent animal study, researchers observed that
vitamin B12 supplementation enhanced the efficiency of cellular reprogramming in mice. It’s hoped that
cellular reprogramming could serve as a new tool for repairing damaged tissues and fighting chronic disease.

Nature Metabolism, November 2023
More Than a Third of Married Couples Share Hypertension. 

According to a recent study, 38% of married middle-aged and older adults in the United States with hypertension have a spouse who also has
high blood pressure. The authors of the study note that married couples often share interests, living environments, and lifestyle habits, some of which may be associated with an elevated risk for hypertension.

Journal of the American Heart Association, December 2023
Vitamin D Supplement May Help Periodontal Care. 

In this study, researchers observed that chronic gum disease patients with low vitamin D status who received a daily 2,000 IU
vitamin D supplement for 90 days experienced an improved response to periodontal treatment. The finding
suggests that vitamin D levels should be assessed in patients seeking care for gum disease.

Georgian Medical News, October 2023
Mediterranean Diet Improves Artery Flexibility. 

According to a recent study, switching to the
Mediterranean diet—an eating pattern focused on fruits, vegetables, nuts, fish, olive oil, and whole grains while
avoiding red and processed meats, dairy, saturated fats, and refined sugars–can reduce proximal aortic stiffness
by 4.8% within 18 months. 

Journal of the American College of Cardiology, April 2023 
Drinking Alcohol Offers No Health Benefits. 

According to a literature review that included
107 studies, moderate alcohol consumption offers no health benefits, and at best, it has no effect on an
individual's health. However, the authors note that averaging three or more drinks a day can significantly
increase the risk of early death from causes that include liver disease, some cancers, stroke, heart disease,
accidents, automobile collisions, homicide, and suicide. 

JAMA Network Open, March 2023
Being Fit Can Reduce Some of the Effects of High Blood Pressure. 

A study that monitored 2,280
middle-aged men found that those with hypertension and low fitness levels were 74% more likely to die due to
cardiovascular disease in the following three decades than hypertensive participants with high fitness levels.
Study author Dr. Jari Laukkanen adds, “Getting blood pressure under control should remain a goal in those with
elevated levels. Our study indicates that men with high blood pressure should also aim to improve their fitness
levels with regular physical activity. In addition to habitual exercise, avoiding excess body weight may enhance
fitness.” 

European Journal of Preventive Cardiology, March 2023
Phospholipids May Promote Atherosclerosis. 

A recent animal study found that at high enough levels,
phospholipids—fats that contain phosphorus that are commonly found in food sources like eggs, organ meats,
lean meats, fish, shellfish, cereal grains, and seed oils—may dysregulate communication between the gut
microbiome and the immune system, stimulating inflammation that can lead to hardening of the arteries.

Journal of Lipid Research, May 2023
AI Might Boost Detection of A-Fib. 

Atrial fibrillation (A-Fib) is a common heart
rhythm disorder in which the upper and lower chambers of the heart intermittently beat out of sync, which can
make it difficult to detect. Researchers have designed an artificial intelligence (AI) agent capable of detecting
subtle changes in heart rhythms on cardiac ultrasounds that are typically overlooked by cardiologists. With
further refinement, AI could soon assist doctors in more accurately diagnosing A-Fib.

NPJ Digital Medicine, May 2024
Anger's Impact on Heart Health. 

New research suggests that angry states can inhibit blood
vessel dilation, potentially damaging blood vessels and raising the risk for future heart disease. The findings
highlight the importance of strategies like exercise, yoga, deep breathing, and cognitive behavioral therapy to
stay calm in the face of stressors. 

National Heart, Lung, and Blood Institute, May 2024
Healthy Living Counters Genetic Risks for Longer Life.

For individuals at high genetic risk for a shorter lifespan, a recent study found that a healthy lifestyle—not smoking, regular exercise, good sleep, and a nutritious diet—can extend longevity by up to 5.5 years.

BMJ Evidence Based Medicine, April 2024
Smart Contact Lenses Detect Glaucoma.

Glaucoma is a group of eye disorders that can damage the optic nerve, leading to vision loss, though symptoms may not be apparent until irreversible vision loss occurs. It’s estimated that three million Americans have glaucoma, but only half are aware they have the condition. Researchers are currently testing a smart contact lens that can measure eye pressure independent of temperature variations, which may help detect glaucoma early on before symptoms develop.

ACS Applied Materials & Interfaces, April 2024
Aspirin Monotherapy May Not Benefit Atrial Fibrillation Patients.

While current guidelines only recommend a daily low-dose aspirin for the prevention of heart attack and stroke in individuals with a history of heart disease, a recent study found that aspirin monotherapy did not reduce the risk for major adverse cardiac and cerebrovascular events in atrial fibrillation (AF) patients. However, the patients who took a daily low-dose of aspirin did experience an elevated risk for bleeding events. The authors conclude, “Patients with AF are unlikely to benefit from aspirin monotherapy.”

International Journal of General Medicine, May 2024
Depression Affects 1 in 3 Menopausal Women.

Following an analysis of data from 55 studies, researchers report that prevalence of depression among women undergoing menopause is roughly 33%.

Journal of Affective Disorders, May 2024
Acid-Reducing Drugs Linked to Increased Migraine Risk?

Researchers from University of Maryland, College Park warn that individuals who use proton pump inhibitors, H2 blockers, and antacids to manage heartburn may have a 30-70% increased risk for migraine headaches and severe headaches. The authors of the study note that additional research is needed to explore the relationship between acid-reducing drugs and migraine.

Neurology, March 2024
Antipsychotics Increase Risk of Serious Health Issues in Dementia Patients.

It’s estimated that up to 30% of dementia patients are prescribed antipsychotic medications to help manage behavioral and psychological symptoms that can accompany the disease. However, a recent study found that antipsychotic drugs can significantly increase the risk for stroke, blood clots, heart attack, heart failure, bone fractures, pneumonia, and kidney damage in patients with dementia. The authors conclude that the widespread use of these drugs in the dementia patient population should be reconsidered and safer alternatives explored.

BMJ, April 2024
Physical Activity Reduces Atrial Fibrillation Risk in Type 2 Diabetics.

Past research has shown that type 2 diabetics are at elevated risk for developing atrial fibrillation, a heart rhythm disorder that can lead to stroke, heart failure, and other cardiovascular complications. In a recent study, researchers observed that diabetics who engaged in at least 214 minutes a week of moderate-intensity physical activity a week had a lower incidence of atrial fibrillation than less active diabetes patients.

Cardiovascular Diabetology, March 2024
Swap Red Meat for Forage Fish?

According to a recent study, swapping red meat in the diet for forage fish—omega-3 fatty acid, calcium, and vitamin B12-rich fish such as anchovies, herring, and sardines—could save hundreds of thousands of lives a year by reducing the incidence of heart disease, stroke, diabetes, and bowel cancer.

BMJ Global Health, April 2024
Light Levels May Affect Cognitive Performance.

With the aid of functional magnetic resonance imaging (fMRI), researchers observed that high-intensity light can increase activity of the hypothalamus, which can positively influence cognitive performance. It’s hoped these findings can help develop light therapy treatment for individuals experiencing cognitive decline.

eLife, April 2024
One Avocado a Day…

Researchers from Penn State report that adding one avocado a day to an individual’s diet may be associated with the following benefits: reduced consumption of unhealthy foods, increased vegetable intake, and a lower risk for heart disease and other chronic conditions.

Current Developments in Nutrition, April 2024
Green Spaces Lower Osteoporosis Risk.

Using data from the UK Biobank study, researchers report that residents of neighborhoods with more greenery may have a 5% lower risk for osteoporosis. The researchers speculate this may be due to the effect greenspaces can have on reducing air pollution, which can benefit bone health, as well as an increase in physical activity that previous studies have associated with greater access to parks and natural spaces.

Annals of the Rheumatic Diseases, March 2024
Bi-Directional Relationship Between Acid Reflux and Sleep Disorders.

A meta-analysis of data from 22 studies concluded that insomnia, sleep disturbance, or short sleep duration double the risk for gastroesophageal reflux disease (GERD), while acid reflux raises the risk for poor sleep by nearly 50%. The findings suggest that patients with sleep troubles should be screened for GERD and vice versa.

PeerJ, April 2024
Exercise Boosts Beneficial Hormone in Breast Milk.

Adiponectin is a metabolic hormone that helps regulate glucose levels and fatty acid breakdown. In a recent study, researchers observed that new mothers who engaged in vigorous exercise experienced an increase in adiponectin in their breast milk that can benefit the metabolism of their offspring, potentially reducing the risk for childhood obesity.

Frontiers in Nutrition, December 2023
Active Lifestyle During Menopause May Protect Brain Health.

New research suggests that women who make an effort to lead an active lifestyle—more time performing physical activity of any intensity and less time engaged in sedentary behaviors— during menopause are less likely to develop dementia later in life.

International Journal of Sports Medicine, April 2024
Vitamin D Status and Type 2 Diabetes.

Using data from the SUN Project study, researchers observed that participants who maintained low vitamin D levels were more likely to develop type 2 diabetes in the following decade. On the other hand, those with healthy vitamin D status were less likely to be diagnosed with type 2 diabetes.

Journal of Endocrinological Investigation, March 2024
Healthy Eating Slows Ageing.

The Mediterranean-DASH Intervention for Neurodegenerative Delay (MIND) diet is an eating pattern that is intended to slow or delay the neurodegenerative decline observed in Alzheimer’s disease patients. In a recent study, researchers observed that adherence to such a diet is associated with slower biological aging, as measured by changes in DNA methylation patterns.

Annals of Neurology, March 2024
Sweetened Beverages Linked to Atrial Fibrillation.

An analysis of data concerning more than 200,000 adults revealed that consuming more than two liters of either sugar-sweetened or artificially sweetened beverages a week is linked to a 10-20% increased risk for atrial fibrillation diagnosis in the next decade. Meanwhile, drinking a liter a week of pure fruit juice can cut the risk for heart arrhythmia disorder by 8%.

Circulation: Arrhythmia and Electrophysiology, March 2024
Many Older Americans Take Daily Aspirin Despite Updated Guidelines.

While current guidelines only recommend a daily low-dose aspirin for the prevention of heart attack and stroke in individuals with a history of heart disease, a recent study found that 60% of regular aspirin users lack such history and may be placing themselves at unnecessary risk for bleeding.

University of Michigan, March 2024
What Are “Naked” Carbs?

Individuals looking to make healthier food choices may be confused by the term naked carbs. In essence, naked carbs are added sugars found in sugary drinks and pre-packaged snacks that cause a rapid spike in blood sugar levels when consumed. On the other hand, dressed carbs are those found in whole foods accompanied by vitamins, minerals, and dietary fiber that are absorbed more slowly into the body without a corresponding spike in blood sugar levels.

The Conversation, March 2024
Mediterranean Diet May Preserve Kidney Health in Diabetics.

Advanced glycation end products (AGEs) form when proteins and fats combine with sugars in the bloodstream and can contribute to various diseases if they’re not efficiently broken down by the kidneys. A study that monitored 500 type 2 diabetics for five years found that those who most closely adhered to the Mediterranean diet had lower blood levels of advanced glycation end products (AGEs), suggesting better kidney function.

Diabetes & Metabolism, January 2024
Cardiovascular Diseases and Dementia.

A review of findings from 25 meta-analyses concluded that coronary heart disease, heart failure, and atrial fibrillation are associated with an elevated risk for dementia and that steps taken in early and midlife to reduce the risk for cardiovascular disease could also reduce the overall risk for dementia.

Frontiers in Epidemiology, February 2024
Physical Activity Protects Kidney Health of Diabetics.

Past research has shown diabetics to be at increased risk for chronic kidney disease. However, a recent study found that engaging in moderate-to-vigorous physical activity for at least one hour a week can reduce this risk by 33%, and exercising for at least 67 minutes a day, seven days a week may potentially mitigate the risk for chronic kidney disease entirely.

BMJ, February 2024
Poor Metabolic Health Raises Cancer Risk.

A study that monitored the health histories of more than 44,000 cancer patients revealed that a decline in metabolic health—worse measurements with respect to body mass index, blood pressure, cholesterol, waist circumference, etc.—is associated with a 27% elevated risk for cancer, particularly breast, endometrial, renal, liver, and colorectal cancers.

Cancer, March 2024
Water-Based Exercise for Nonspecific Chronic Low-Back Pain?

Chronic low back pain patients are often encouraged to exercise as part of the recovery process but there is debate on which forms of exercise may be of most benefit. For patients who enjoy being in the water, a systematic review that included 15 studies found that water-based exercise therapy is equally as effective as land-based exercises for reducing pain and improving function in patients with non-specific chronic low back pain.

Journal of Strength & Conditioning Research, January 2024
Smoking and Back Pain.

Using data from the UK Biobank study, researchers report that smoking is a risk factor for low back pain. On the other hand, quitting smoking can reduce one’s risk for low back pain over time.

Journal of Global Health, November 2023
Improving Fitness Lowers Prostate Cancer Risk.

New research suggests that improving cardiorespiratory fitness by 3% each year can reduce the risk for prostate cancer in the next seven years by 35%.

British Journal of Sports Medicine, January 2024
Modifiable Risk Factors for Neurocognitive Disorders.

An umbrella review that included 45 systematic reviews and 212 meta-analyses identified the following modifiable risk factors for neurocognitive disorders, which includes mild cognitive impairment and dementia: excessive alcohol consumption, obesity, depression, diabetes mellitus, poor diet, hypertension, less educational attainment, physical inactivity, sensory loss, sleep disturbance, smoking, social isolation, traumatic brain injury, and vitamin D deficiency.

Dementia and Geriatric Cognitive Disorders, February 2024
Dried Fruit May Lower Alzheimer's Risk.

Following an analysis of data concerning more than 450,000 adults, researchers report that a high intake of dried fruit is associated with up to a 12% reduced risk for Alzheimer's disease.

Nutritional Neuroscience, February 2024
Combined Exercise Intervention Reduces Risk for Serious Events in Liver Cirrhosis Patients.

An analysis of data from 11 randomized controlled trials revealed that patients with liver cirrhosis who engage in a fitness program that combines resistance and aerobic training are four times less likely to experience serious events such as portal hypertension, ascites, hepatic encephalopathy, spontaneous bacterial peritonitis, hepatorenal syndrome, liver cancer, jaundice, gastrointestinal bleeding, and coagulopathy.

Journal of Gastroenterology, December 2023
Alcohol- and Drug-Related Heart Deaths Are Increasing Among Americans.

While the incidence of death from heart disease has fallen in recent decades, researchers have observed that heart disease deaths linked to drug or alcohol use have risen 6% each year since 2012 with alcohol accounting for two-thirds of such deaths.

Journal of the American Heart Association, January 2024
Beans Benefit Colorectal Cancer Survivors.

Researchers from the University of Texas MD Anderson Cancer Center report that individuals with a history of colorectal neoplasia may be able to improve the health of their digestive tract and potentially reduce the risk of recurrence by consuming one cup of navy beans a day.

eBioMedicine, December 2023
Childhood Diet Can Lead to Blood Vessel Damage.

University of Bristol researchers report that boys and girls who consume a diet high in calories, fat, and sugar and low in fiber before adolescence are more likely to exhibit stiffening of the arteries at age 17, which can increase the risk for heart attack and stroke before midlife.

British Journal of Nutrition, January 2024
One-in-Fifty Young Kids Is Severely Obese.

After falling from 2.1% in 2010 to 1.8% in 2016, the rate of severe obesity among young children in the United States has risen to 2%. The finding is alarming as being overweight early in life often leads to poor lifestyle choices in adolescence and young adulthood that not only increase the risk for chronic disease but also diagnosis at younger ages.

Pediatrics, December 2023
Exhaust Pollution Linked to Diabetes Risk.

Fine-particulate matter is a mixture of dust, dirt, soot, smoke, and liquid droplets in the air, most commonly from gasoline combustion and burning wood and coal. An analysis of data concerning nearly 20,000 adults found that frequent exposure to high levels of fine-particular matter air pollution can double an individual’s risk for type 2 diabetes.

Environmental Geochemistry and Health, January 2024
Physical and Social Activities Benefit the Ageing Brain.

University of Zurich researchers report that more physically and socially active individuals exhibited less reduction in thickness of the entorhinal cortex over a seven-year period, which is a sign of healthy brain aging.

University of Zurich, December 2023
Loneliness Raises Cardiovascular Event Risk in Diabetics.

Using data from the UK Biobank study, researchers found that type 2 diabetics who experience elevated levels of social isolation and loneliness have about a 36% increased risk for adverse cardiovascular events, including heart attack and stroke.

General Psychiatry, December 2023
Pulse Pressure Hints at Cardiovascular Risks.

Pulse pressure is the difference between the two numbers in a blood pressure reading, which can aid in assessing arterial stiffness. An analysis of data concerning more than 65,000 adults revealed that for every 10-point increase in pulse pressure, the risk for heart attack, stroke, and premature death rises by 11%.

American Journal of Preventative Cardiology, November 2023
Early Onset Heart Disease Hints at Future Dementia.

An analysis of long-term health data concerning more than 450,000 older adults revealed that poor cardiovascular health at age 45 is associated with a 25% increased risk for dementia diagnosis later in life.

Journal of the American Heart Association, November 2023
Brain Inflammation May Trigger Anger and Anxiety in Alzheimer’s Patients.

Examinations of 109 Alzheimer's disease patients revealed that brain inflammation, and not traditional markers of the disease like amyloid beta or tau proteins, may be the primary cause of rapid changes in mood and distress that frequently accompany the condition. The findings suggest that lifestyle changes or direct treatment aimed at reducing inflammation in the brain may reduce the severity of mood disorders in Alzheimer's patients.

JAMA Network Open, November 2023
Poor Metabolic Health Can Hinder Breast Cancer Treatment.

Among a sample of 955 breast cancer patients treated at hospitals in Naples, Italy between 2009 and 2013, researchers observed the risk for breast cancer-related mortality increased 61% in patients with metabolic syndrome. The findings suggest that metabolic syndrome may impair the effectiveness of breast cancer therapies, implying that improving metabolic health should be a priority in these patients.

Scientific Reports, December 2023
Exercise Reduces Risk for Early Death.

Meeting physical activity recommendations of at least 150 minutes of moderate-intensity physical activity a week can reduce the risk of early death in the following eight years by up to 25%.

Diabetology & Metabolic Syndrome, December 2023
Following Life's Essential 8 May Slow Biological Aging.

The American Heart Association’s Life’s Essential 8 is a collection of traits—not smoking, good sleep hygiene, healthy weight, healthy diet, regular exercise, and healthy blood glucose, cholesterol, and blood pressure levels—linked to a reduced risk for cardiovascular disease. New research suggests that individuals with greater adherence to the Life’s Essential 8 checklist have a biological age up to six years younger than their actual age.

American Heart Association, November 2023
Greenery May Curb Dementia Risk.

Using data from the UK Biobank study, researchers report that the more greenspace that exists within a 300-meter radius of an individual’s home, the lower their risk for dementia diagnosis in the following decade of life.

Science of the Total Environment, November 2023
Combustion Exhaust and Stroke.
Fine-particulate matter is a mixture of dust, dirt, soot, smoke, and liquid droplets in the air, most commonly from gasoline combustion and burning wood and coal. During a twelve-year study that included more than 40,000 adults, researchers observed that participants who lived in areas with greater exposure to fine-particulate matter air pollution had nearly a four-time greater risk for stroke than those residing in areas with minimal particulate matter levels.

Stroke, November 2023
Depression Can Be Deadly for Diabetics.

According to a recent study that included nearly 15,000 adults, researchers found that those with either type 1 or type 2 diabetes and depression had a greater risk for early death than those with one or neither condition. The findings suggest that diabetic patients should be screened for concurrent depression.

Diabetes & Metabolic Syndrome: Clinical Research & Reviews, October 2023
Ultra-Processed Food Products May Worsen Health.

Ultra-processed foods and food products include added sugars, fats, and salt to enhance flavor and prolong shelf life. A recent literature review noted more than 70 studies have linked a high intake of ultra-processed food with both weight gain and an elevated risk for several chronic diseases. This is alarming as experts estimate that half of the average American’s daily caloric intake comes from ultra-processed food products.

BMJ, October 2023
High-Intensity Exercise May Protect Against Alzheimer’s.

An analysis of data from 29 studies that included more than 2 million participants revealed that regularly engaging in high-intensity physical activity may reduce the risk for Alzheimer’s disease by nearly 50%.

Ageing Research Reviews, November 2023
Nutrients That Benefit the Eyes. 

The American Academy of Ophthalmology notes the following nutrients are essential for eye health: vitamin A, vitamin C, vitamin E, omega-3 fatty acids, lutein, zeaxanthin, zinc, and copper. 

American Academy of Ophthalmology, October 2023
Exercise Recommendations During Cancer Treatment.

To help combat some common side effects of cancer treatment including fatigue, lymphedema, anxiety, depressive symptoms, and worse physical function, clinical guidelines recommend patients engage in 75 minutes of vigorous-intensity or 150 minutes of moderate-intensity physical activity a week spread over at least two sessions.

Supportive Care in Cancer, November 2023
Endurance Training Changes How Genes Express in Muscles.

In a recent animal study, researchers observed that regular endurance training activates certain genes in muscle cells that stimulate them to work more efficiently and be more resilient to mechanical stress.

Nature Metabolism, September 2023
Exercise Helps Patients with Lynch Syndrome.

Lynch syndrome is a condition characterized by a genetic predisposition for several cancers, including colorectal cancer. In a recent study, researchers observed that Lynch syndrome patients who engaged in high-intensity interval training experienced a reduction in inflammation and an increase in certain immune cells that may reduce their cancer risk.

Clinical Cancer Research, September 2023
Fats and Inflammation in the Brain.

In a recent laboratory study, investigators observed that exposing certain brain cells to saturated fats stimulated an inflammatory response that can affect memory formation. However, initially treating the brain tissue with omega-3 fatty acids appears to inhibit much of the inflammation caused by the saturated fats.

Frontiers in Cellular Neuroscience, August 2023
Amino Acid May Reduce Stroke Risk.

Using data from the European Prospective Investigation into Cancer and Nutrition (EPIC) study, researchers report that a high intake of proline—an amino acid found in protein-rich foods—is associated with a 12% reduced risk for ischemic stroke.

European Journal of Nutrition, October 2023
High Blood Pressure in Teen Years Can Cause Lifelong Issues.

According to a recent study that looked at long-term data concerning 1.3 million Swedish adults, elevated blood pressure readings at age 18 are associated with up to a 71% increased risk for myocardial infarction, heart failure, ischemic stroke, or intracerebral hemorrhage later in life. The findings highlight the need for interventions to reduce obesity, unhealthy diet, and physical inactivity among today’s youths—lifestyle factors that are each associated with poor cardiovascular health, including high blood pressure.

Annals of Internal Medicine, September 2023
Walk More.

The Mayo Clinic reports that taking regular walks can offer one avenue for meeting physical activity guidelines of 150 minutes a week, which can benefit both heart health and mental wellbeing.

Mayo Clinic, September 2023
Eye Scans Could Spot Parkinson's Earlier.

University College London and Moorfields Eye Hospital researchers report that optical coherence tomography scans are capable of detecting subtle changes in the eyes that develop very early in the course of Parkinson’s disease progression, up to seven years before the condition may even be diagnosed.

Neurology, August 2023
Microbiome Diversity May Protect Kids from Asthma.

Examinations of 320 young children revealed that those with a more mature and diverse gut microbiome at one year of age were less likely to develop allergy-related wheezing and asthma by age four. Past research has shown an association between a healthy gut microbiome and better immune function, which may protect against inflammatory conditions like asthma.

European Respiratory Society, September 2023
Lynch Syndrome and Dietary Behaviors…

Lynch syndrome is a condition characterized by a genetic predisposition for several cancers, including colorectal cancer. Despite this, a recent study that included 280 individuals with lynch syndrome found that, although these patients are aware of their increased risk for several cancers, they tend to consume less dietary fiber, fruit, and vegetables, and more red and processed meat than the general population. The findings suggest that adults with lynch syndrome may be able to reduce their cancer risk by adopting a healthier diet pattern.

Clinical Nutrition ESPEN, October 2023
Age of Puberty May Help Predict Diabetes and Obesity Risk in Middle Age.

Using data from the Tabari cohort study, researchers report for each year before age 14 that a female starts puberty, her risk for diabetes, obesity, and central obesity during midlife increases by 5%, 10%, and 5%, respectively.

Frontiers in Cardiovascular Medicine, September 2023
Web-Based Nutrition Program Benefits Type 2 Diabetics.

For patients with type 2 diabetes, a recent study found that adding a web-based low carbohydrate nutrition program to usual care helped participants better control their blood sugar levels, which allowed 25% of them to reduce their medication used by more than 20%.

Nutrition & Diabetes, August 2023
Gastrointestinal Symptoms May Be Indicator for Parkinson’s.

Parkinson's disease is a progressive neurological disorder that can cause tremors, difficulty with movement, impaired balance and coordination, and muscle rigidity. A recent study found that individuals with gastrointestinal symptoms such as constipation, difficulty swallowing, delayed stomach emptying (gastroparesis), and irritable bowel syndrome without diarrhea may be at elevated risk for Parkinson’s diagnosis in the next five years.

Gut, August 2023
Half of People with Glaucoma Don’t Know They Have It!

Glaucoma is a group of eye disorders that can damage the optic nerve, leading to vision loss, though symptoms may not be apparent until irreversible vision loss occurs. It’s estimated that three million Americans have glaucoma, but only half are aware they have the condition. Health experts remind adults over age 50 or those with a family history of glaucoma to attend regular eye exams because while there’s no known cure, treatment can help control the disease and slow its progression if caught early.

Penn State Health, July 2023
Healthy Diet Lowers Heart Disease Risk for Diabetics.

Using data from the UK Biobank study, researchers report that diabetics who switch to a healthy diet pattern—such as the Mediterranean diet or DASH diet—can reduce their risk for cardiovascular disease by nearly 30% over a ten-year period.

Food & Function, September 2023
Omega-3 Fatty Acid May Help Preserve Brain Function.

Among a group of 3,564 older adults, researchers observed that those who maintained higher blood levels of docosapentaenoic acid, an omega-3 fatty acid found in cold-water fatty fish, had a lower risk for cognitive decline over the following two decades.

Journal of Alzheimer's Disease, August 2023
Good Diabetes Management Can Reduce Heart Attack Risks.

Using Taiwan's Longitudinal Cohort of Diabetes Patient Database, researchers found that type 2 diabetics who do a better job at managing the disease—getting regular check-ups and maintain healthy blood glucose, blood pressure, and blood lipid levels—were up to 63% less likely to suffer a heart attack in the next decade.

World Journal of Diabetes, July 2023
Diet May Be Key to Preventing Hospitalization-Associated Disability.

In addition to engaging in a physical exercise intervention during a hospital stay, researchers report that adhering to a healthy diet pattern, such as the Mediterranean diet, can reduce the risk for physical deterioration and weakness, which can affect a patient’s ability to carry out activities of daily living upon discharge.

Journal of Nutrition, Health & Aging, July 2023
Too Much TV in Childhood Can Set the Stage for Metabolic Syndrome...

Metabolic syndrome is a cluster of conditions—obesity, high blood pressure, abnormal cholesterol, impaired metabolic function, and excessive waist circumference—that occur together and elevate the risk of heart disease, stroke, and type 2 diabetes. A study that monitored more than 1,000 New Zealanders born in the early 1970s found that those who spent more time watching television as kids were more likely to have metabolic syndrome at age 45.

Pediatrics, July 2023

Congestive Heart Failure--Traditional and Alternative Approach

Heart failure — sometimes known as congestive heart failure — occurs when the heart muscle doesn't pump blood as well as it should. When this happens, blood often backs up and fluid can build up in the lungs, causing shortness of breath.
Heart failure signs and symptoms may include:
Shortness of breath with activity or when lying down
Fatigue and weakness
Swelling in the legs, ankles and feet
Rapid or irregular heartbeat
Reduced ability to exercise
Persistent cough or wheezing with white or pink blood-tinged mucus
Swelling of the belly area (abdomen)
Very rapid weight gain from fluid buildup
Nausea and lack of appetite
Difficulty concentrating or decreased alertness
Recommended testing for Heart Failure:
NT-proB-type Natriuretic Peptide (BNP) blood test. B-type natriuretic peptide (BNP) is a hormone produced by your heart. Levels goes up when heart failure develops or gets worse, and levels goes down when heart failure is stable. In most cases, BNP and NT-proBNP levels are higher in patients with heart failure than people who have normal heart function.
A normal level of NT-proBNP, based on Cleveland Clinic's Reference Range is:
Less than 125 pg/mL for patients aged 0-74 years
Less than 450 pg/mL for patients aged 75-99 years
If you have heart failure, the following NT-proBNP levels could mean your heart function is unstable:
Higher than 450 pg/mL for patients under age 50
Higher than 900 pg/mL for patients age 50 and older
Echocardiogram
Ejection fraction (EF): Your EF is a measurement of the blood pumped out of your heart with each beat. A normal EF is between 55% and 70%
The Role of C-Reactive Protein (CRP) in Heart Failure
Some studies show that CRP is increased in heart failure. Higher levels are associated with features of more severe heart failure and are independently associated with mortality and morbidity.

Traditional Medical Treatments:
The newer combination drug called Sacubitril-valsartan (Entresto) (called an ARNI, ARB with a Neprilysin Inhibitor) has been studied and shown to have improved outcomes in patients with a weak heart muscle when it replaces medications like lisinopril (an ACE Inhibitors) or losartan (an ARB, or Angiotensin Receptor Blocker). For patients with a heart muscle with reduced ejection fraction (EF< 40%), Quadruple therapy is the recommended:
An ACE Inhibitor, ARB or ARNI
A Beta blocker (carvedilol or metoprolol succinate)
An Aldosterone antagonist (spironolactone or eplerenone)
An SGLT2 Inhibitor (dapagliflozin)

Diet for Lowering Metabolic Syndrome Risk.

Metabolic syndrome is a cluster of conditions—obesity, high blood pressure, abnormal cholesterol, impaired metabolic function, and excessive waist circumference—that occur together and elevate the risk for heart disease, stroke, and type 2 diabetes. Using data from the 2014-2018 Korean National Health and Nutrition Examination Survey, researchers report that a high-fat, low-carbohydrate diet pattern is associated with a reduced risk for metabolic syndrome.

Iranian Journal of Public Health, April 2023
Pupil Size May Help Find Best Exercises for Brain Health.

Executive functions are a collection of mental skills—working memory, reasoning, multi-tasking, problem-solving, and planning skills—that help the brain organize and act on information. In a recent experiment, researchers observed that increases in pupil size during light exercise could serve as a biomarker to gauge the effectiveness of a physical activity intervention on enhancing executive function skills, helping to pinpoint which exercise techniques may best benefit a particular individual’s cognitive health.

NeuroImage, July 2023
Vitamin D Supplements May Improve Diabetes Management.

Using data from 38 studies, researchers report that adding vitamin D supplementation to standard type 2 diabetes care can significantly improve serum insulin and glucose reading and reduce insulin resistance.

Scientific Reports, July 2023
Sedentary Lifestyle Carries Risks.

A systematic review that included 18 studies found that individuals who fail to meet physical activity guidelines and frequently engage in prolonged bouts of sedentary behaviors may be at elevated risk for several non-communicable diseases (including heart disease, cancer, chronic respiratory disease, and diabetes) and even early death. In addition to regular exercise, the authors of the study encourage everyone to reduce sedentary time and to get up and move around every 30-60 minutes to break up prolonged sedentary sessions.

International Journal of Nursing Studies, July 2023
Low-Dose Aspirin May Raise Anemia Risks Among Older Adults.

Anemia is a condition caused by low levels of iron in the blood, which can lead to symptoms such as fatigue and a decline in overall function in older people. A recent study found that taking a daily low-dose aspirin may raise the risk for anemia in seniors by more than 20%. The findings highlight the need for careful consideration of the potential risks and benefits of aspirin use in older adults.

Annals of Internal Medicine, May 2023
Cardiorespiratory Fitness Protects Memory.

McGill University researchers report that individuals with higher cardiorespiratory fitness levels perform better on memory assessments following a period of sleep deprivation than their peers with poor fitness. The findings suggest that fitness can protect the brain from some of the effects of sleep loss, which may be especially relevant for individuals in professions that require sustained wakefulness and optimal memory performance.

Medicine & Science in Sports & Exercise, June 2023
Exercise with Weight Loss Helps Fight Diabetes.

For individuals at risk for diabetes, losing 10% of body weight and getting regular exercise can dramatically improve insulin sensitivity compared with weight loss alone. The findings suggest that prediabetics should focus on incorporating physical activity into their lifestyle in addition to losing excess weight to delay or prevent diabetes.

Nature Metabolism, June 2023
Exercise for Type 2 Diabetics.

Experts recommend that type 2 diabetics engage in an exercise program that includes both aerobic and resistance training components, as aerobic exercises like cycling, jogging, and swimming can help manage blood glucose and working the muscles can improve insulin sensitivity. In addition to regular exercise, it’s important for diabetics to avoid prolonged sedentary time, which is associated with several poor health outcomes.

American Journal of Medicine Open, June 2023
Are “Sports” Foods Accurately Labeled?

Evaluations of 558 food products marketed toward athletes in New Zealand revealed that a third did not list accurate nutritional data on their packaging. Additionally, the majority of the bars, gels, drinks, and powders researchers looked at made inaccurate claims and/or failed to include required warning or advisory statements.

Frontiers in Nutrition, February 2023
Low or High BMI May Be Dementia Risk Factor for Women.

An eight-year study that monitored more than 13,000 middle-aged and older adults found that women who are either underweight or overweight, as per their body mass index (BMI), may be two times more likely to develop dementia as their peers who maintain a normal weight.

Journal of Alzheimer’s Disease, June 2023
Physical Activity and Better Cognitive Function.

Among a group of 647 older adults, researchers observed an association between higher levels of physical activity and better scores on cognitive assessments in the domains of visual space, attention, language, abstract ability, and delayed recall.

Frontiers in Aging Neuroscience, June 2023
Diet and Metabolic Syndrome.

Metabolic syndrome is a cluster of conditions—obesity, high blood pressure, abnormal cholesterol, impaired metabolic function, and excessive waist circumference—that occur together and elevate the risk for heart disease, stroke, and type 2 diabetes. An analysis of data from the Korean National Health and Nutrition Examination Survey revealed that a high-carbohydrate diet is associated with an elevated risk for metabolic syndrome in women, while a high-fat diet is linked to an increased risk for the condition in men.

Nutrients, June 2023
How Added Sugars May Worsen IBD...

Patients with inflammatory bowel disease (IBD) are often advised to avoid foods with added sugars as they can exacerbate symptoms. According to a recent animal study, a high-sugar intake can negatively affect the growth and division of the epithelial cells that protect the colon, stimulating inflammation.

Cellular and Molecular Gastroenterology and Hepatology, May 2023
Breastfeeding and Higher Test Scores?

Adding to a growing body of research on the benefits of breastfeeding, a study that monitored the progress of nearly 5,000 children revealed that those breastfed for at least twelve months tended to score higher on assessments of both mathematics and English than participants breastfed for less than a year or not at all.

Archives of Disease in Childhood, June 2023
What You Should Know About Cataracts.

A cataract is a clouding of the eye’s lens that will affect at least half of all adults by age 80 and can cause blindness if left untreated. Early symptoms may include cloudy or blurry vision, faded colors, difficulty seeing at night, and the perception of halos around lights. If you’re experiencing any of these symptoms, please contact your ophthalmologist or optometrist.

Prevent Blindness, May 2023
How Much Protein Is Needed Per Day?

The Academy of Nutrition and Dietetics notes that the recommended daily protein intake can vary based on factors like age, sex, weight, activity level, and health. However, most healthy adults are advised to consume about 0.8 grams of protein per kilogram of body weight (or 0.36 grams per pound). For those with a more physically active lifestyle, the recommendation may increase to a range of 1.2 to 2.2 grams per kilogram of body weight (or 0.54 to 1 gram per pound). The academy adds that individuals should consult with their healthcare provider or dietician to determine their specific protein requirements based on their unique circumstances.

Academy of Nutrition and Dietetics, May 2023
Diabetes Before Pregnancy is Becoming More Common.

The Centers for Disease Control and Prevention reports that the rate of pregnancies involving women with diabetes increased from 9 per 1,000 births to 11 per 1,000 births—a 27% increase—between 2016 and 2021. Health experts warn that diabetes during pregnancy should be carefully managed as it’s associated with an increased risk for several complications including birth defects, Cesarian birth, preeclampsia, abnormal birth weight, miscarriage, stillbirth, perinatal/postpartum depression, preterm labor, preterm birth, birth trauma, autism spectrum disorder, jaundice, hypoglycemia, respiratory distress syndrome, and more.

National Vital Statistics Reports, May 2023
Decreasing Chemical Tied to Parkinson's Disease.

Trichloroethylene (TCE) is a chemical commonly used for industrial degreasing. In a recent study, researchers observed that individuals heavily exposed to TCE for at least two years have a 70% increased risk for developing Parkinson’s disease.

JAMA Neurology, May 2023
Healthier Diet Improves Fitness.

A study that looked at the health and lifestyle history of more than 2,000 adults concluded that eating a healthy diet provides the same fitness benefits as walking an extra 4,000 steps a day. The finding suggests that better metabolic health may contribute to physical fitness.

European Journal of Preventive Cardiology, April 2023
What Are Ultra-Processed Foods?

Ultra-processed foods are food products that include added sugars, fats, and salt to enhance flavor and prolong shelf life. Examples of ultra-processed foods include packaged cookies, chips, cereals, frozen meals, fast food, and soda. Several studies have linked a diet high in ultra-processed foods with obesity, cardiovascular disease, type 2 diabetes, and some cancers.

Tufts University, May 2023
Dietary Pattern That May Increase Longevity.

An analysis of data from a two-decade study that included more than 350,000 middle-aged and older adults revealed that a low intake of saturated fat and a high intake of plant protein and high-quality carbohydrates is associated with a reduced risk of death from cardiovascular disease and cancer.

Journal of Internal Medicine, May 2023
Childhood Asthma Linked to RSV During Infancy?

Respiratory syncytial virus (RSV) is a seasonal lower respiratory tract infection that affects most children by age two. In a recent study that included more than 1,900 children, researchers found that those who contracted RSV after their first birthday were 26% less likely to develop asthma by age five.

The Lancet, April 2023
Vitamin D May Benefit Carpal Tunnel Syndrome Sufferers.

Researchers note that low vitamin D levels can worsen the symptoms associated with carpal tunnel syndrome and may even be a risk factor for the condition. A systematic review that included 19 studies found that improving vitamin D status with supplementation can benefit CTS patients.

Current Rheumatology Reviews, May 2023
Imagine Eating Junk Food.

Researchers note that studies have shown that imagining eating junk food can activate the same neural networks as the physical act itself, which can help dieters stick to a healthier eating pattern.

Journal of Public Policy & Marketing, May 2023
Children from Smoking Households More Likely to Have Temperament Issues.

Following an analysis of data from the 2019-2020 National Survey of Children's Health, researchers report that kids who live with a smoker are about 50% more likely to be prone to distraction, lose their temper when things don’t go their way, and have trouble both calming down and playing well with their peers.

Journal of Affective Disorders, May 2023
Most Food Purchases Contain Additives.

Using data on consumer food purchases from 2019, researchers report that 60% of items in the average consumer’s shopping cart contained coloring or flavoring agents, preservatives, and/or sweeteners. Similar research conducted on purchases from 2001 found that just 10% of groceries contained such additives.

Journal of the Academy of Nutrition and Dietetics, March 2023
Too Little Sodium May Harm Heart Failure Patients.

To reduce fluid build-up and swelling, heart failure patients are advised to reduce their sodium intake to 2.5 grams a day (most Americans consume 3.4 grams in their daily diet). However, an analysis of data from nine studies found that cutting sodium to less than 2.5 grams a day does not confer additional heart benefits and may even increase the risk of early death. First author Dr. Anirudh Palicherla adds, “Limiting sodium is still the way to go to help manage heart failure, but the amount of restriction has been up for debate… This study shows that the focus should be on establishing a safe level of sodium consumption instead of overly restricting sodium.”

American College of Cardiology, February 2023
Listen to What Some of Our Actual Clients Are Saying...

"NO MORE INSULIN SHOTS"

     John Davidson tells his story about how he reversed his type 2 diabetes in 5 months with Dr. John Heary.
John was diagnosed with type 2 diabetes 20 years ago. He initially started on oral medications for the diabetes and was put on meds for high blood pressure.

     As the diabetes progressed his doctor put him on insulin. He has been on insulin and giving himself shots in the abdomen for the past 13 years. He has been on high blood pressure meds for 17 years.

     In 5 months of starting a program with Dr. John Heary, John Davidson has lost 42 pounds and 19 inches off his waist. His Hemoglobin A1C went from 12.4 to 4.4. His medical doctor declared his type 2 diabetes has been reversed. She has taken him off insulin and his high blood pressure medication.

     I want to congratulate John on his hard work. He has stayed right on track with his program and focused on his goals. He truly is an inspiration and I am looking forward to the continued changes he makes with his health.
Low Vitamin D Status Linked to Poor Cardiometabolic Health in Kids and Teens.

Using data from the long-term IDEFICS/I.Family cohort study, researchers have identified an association between low vitamin D levels in childhood and adolescence and unfavorable blood pressure, fasting glucose, insulin resistance, and blood lipid readings. The authors conclude, “Interventions to improve vitamin D levels in children with a poor status early in life may help to reduce cardiometabolic risk.”

Journal of Clinical Endocrinology and Metabolism, June 2023
Time-Restricted Eating Benefits Blood Glucose and Lipid Readings.

Colorado State University researchers report that restricting eating to an eight-hour window during the day can improve blood glucose and insulin levels, as well as some lipid levels that are linked to metabolic disease.

Colorado State University, May 2023
Taking Longer to Perform Tasks May Be a Sign of Dementia Risk.

Using data from the Perth Longitudinal Study of Aging in Women, researchers report that older women with weaker grip strength and worse performance on the timed-up-and-go test (rise from a chair, walk three meters, turn around, and sit back down) were more likely to develop dementia in the following 15 years, even after controlling for known risk factors for the neurodegenerative condition.

Journal of Cachexia, Sarcopenia and Muscle, April 2023
A Link Between the Gut and High Blood Pressure?

New research suggests that the gut microbiome may have a role to play in the development of hypertension, and steps to improve the health of the gut may someday be included in treatment guidelines for managing high blood pressure. The finding adds to a growing body of research on the relationship between the bacteria in the gut and the function of several key systems in the body.

Clinical and Experimental Hypertension, March 2023
Experiencing Hearing Loss?

The Mayo Clinic notes that signs of hearing loss include muffled speech/sounds; trouble understanding words, particularly in a crowd or noisy environment; difficulty hearing consonants; frequently asking a speaker to repeat what they said; needing to listen to the TV/radio at ever higher volumes; social isolation; and tinnitus. If you regularly experience these symptoms, contact your healthcare provider to arrange for a hearing test.

Mayo Clinic, April 2023
Severe Sleep Apnea May Double Risk for Hospitalization for Pneumonia.

An analysis of data from the Atherosclerosis Risk in Communities study revealed that older adults with severe obstructive sleep apnea (OSA) were nearly two times more likely to be hospitalized for pneumonia during the 20-year study. The authors of the analysis conclude, “OSA patients may benefit from more aggressive efforts to prevent pneumonia and other infectious conditions.”

Chest, April 2023
Strength Training Can Reduce Blood Pressure.

A recent literature review concluded that just eight-to-ten weeks of strength training is sufficient to reduce systolic blood pressure by 10 mmHg and diastolic blood pressure by 4.79 mmHg. Researcher Dr. Giovana Rampazzo Teixeira explains, “In clinical practice and gyms or fitness centers, strength training can be a treatment option for people with high blood pressure as a non-pharmacological intervention as long as you know enough about the key variables and take the subject's goals into account.”

Scientific Reports, March 2023
Omega-3 Fatty Acids May Prevent Some Heart Attacks.

Following an analysis of data from 17 randomized-controlled trials, researchers report that taking an omega-3 fatty acid supplement daily for one year can reduce the risk of heart attack by 17%.

Advances in Nutrition, April 2023
Low-Fat Diet May Lower Heart Attack Odds in At-Risk Patients.

A recent analysis concluded that switching to a low-fat diet may reduce the risk for non-fatal heart attack in individuals with at least two of the following cardiovascular disease risk factors: hypertension, dyslipidemia, obesity, and diabetes mellitus.

BMJ Today, March 2023
Mediterranean Diet Reduces Heart Disease Risk in Women.

The Mediterranean diet is an eating pattern focused on fruits, vegetables, nuts, fish, olive oil, and whole grains while avoiding red and processed meats, dairy, saturated fats, and refined sugars. A systematic review that included 16 studies concluded that close adherence to the Mediterranean diet is linked to a 24% lower risk for heart disease in women.

Heart, March 2023
Dirty Air Linked to Dementia.

Fine-particulate matter is a mixture of dust, dirt, soot, smoke, and liquid droplets in the air, most commonly from gasoline combustion and burning wood and coal. The current research suggests that increased exposure to fine-particulate matter air pollution is associated with an elevated risk for dementia, either by directly affecting cells in the brain or from its impact on cardiovascular function.

BMJ, April 2023
Obesity Increases Risk of Diabetes and Hypertension.

An analysis of data on nearly 11,000 older adults revealed that obesity is associated with an elevated risk for both type 2 diabetes and hypertension. The findings highlight the importance of maintaining a healthy weight throughout life and into old age.

Scientific Reports, February 2023
Is Inflammatory Bowel Disease a Risk Factor for Heart Attack?

Using a data set that included nearly 600,000 adults, researchers report that individuals with either Crohn's disease or ulcerative colitis have a 9-22% increased risk for stroke and a 24-36% elevated risk for heart attack in the next five years.

International Journal of Cardiology, May 2023
Physically Demanding Work May Increase Male Fertility.

According to a recent study, men whose work activities include frequent lifting and moving of heavy objects have higher sperm counts and concentration than those with less physical jobs. First author Dr. Lidia Mínguez-Alarcón writes, “What these new findings suggest is that physical activity during work may also be associated with significant improvement in men's reproductive potential.”

Human Reproduction, February 2023
Parents Often Give Fever Meds to Kids Too Soon.

A survey of nearly 1,400 parents revealed that a third would still give their child fever-reducing medication at a temperature below 100.4 degrees Fahrenheit and half would provide such pharmaceuticals at a temperature below 101.9 degrees Fahrenheit. Additionally, one-in-four parents would give their child an additional dose in an effort to keep such a low-grade fever from returning. Pediatrician Dr. Susan Woolford adds, “Some parents may immediately rush to give their kids medicine, but it's often better to let the fever run its course… Lowering a child's temperature doesn't typically help cure their illness any faster. In fact, a low-grade fever helps fight off the infection. There's also the risk of giving too much medication when it's not needed, which can have side effects.”

University of Michigan, February 2023
Mental Health Among Teens Has Worsened in the Last Decade.

The Centers for Disease Control and Prevention reports that the percentage of teen boys and girls experiencing persistent sadness or hopelessness increased from 21% and 36% in 2011 to 29% and 57% in 2021, respectively.

Centers for Disease Control and Prevention, February 2023
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